Modeling TMJD pain in the laboratory mouse: role of TRP ion channels
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چکیده
منابع مشابه
Modeling TMJD pain in the laboratory mouse: role of TRP ion channels
Trigeminal pain syndromes such as temporomandibular joint (TMJ) pain appear to have a particular potential to affect patients in a devastating manner. Prevalence of trigeminal pain disorders in the US is estimated at 2030x10, at >50-75x10 including headaches/migraine. Neural circuit malfunction and maladaptive plasticity arise from altered primary sensory afferents. We have focused on a nerve c...
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The transient receptor potential (TRP) superfamily comprises a group of non-selective cation channels that sense and respond to changes in their local environments. TRP channels are found in many eukaryotes, from yeast to mammals. They are a diverse group of proteins organized into six families: classical (TRPC), vanilloid (TRPV), melastatin (TRPM), muclopins (TRPML), polycystin (TRPP), and ANK...
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ژورنال
عنوان ژورنال: Molecular Pain
سال: 2014
ISSN: 1744-8069
DOI: 10.1186/1744-8069-10-s1-o8